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Yuichi Sugiyama Selected Research

troglitazone sulfate

2/2007Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect.

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Yuichi Sugiyama Research Topics

Disease

50Breast Neoplasms (Breast Cancer)
01/2022 - 09/2004
12Neoplasms (Cancer)
08/2017 - 05/2002
5Infections
10/2021 - 01/2002
5progressive familial intrahepatic 1 Cholestasis
05/2014 - 04/2005
5Muscular Diseases (Myopathy)
04/2013 - 10/2006
5Cholestasis
09/2010 - 09/2006
4Hypercholesterolemia
12/2019 - 12/2004
3Rhabdomyolysis
07/2018 - 10/2006
3Diarrhea
08/2017 - 01/2002
3Intrahepatic Cholestasis
07/2013 - 09/2010
3Body Weight (Weight, Body)
01/2010 - 09/2002
2Hyperbilirubinemia
01/2022 - 09/2005
2Neutropenia
08/2017 - 05/2008
2Hepatocellular Carcinoma (Hepatoma)
03/2014 - 05/2002
2Human Influenza (Influenza)
01/2014 - 02/2008
2Ornithine Carbamoyltransferase Deficiency Disease
06/2012 - 05/2012
2Tics (Tic)
05/2012 - 11/2010
2Inborn Urea Cycle Disorders
09/2010 - 01/2009
2Cerebral Infarction
11/2007 - 08/2007
2Chronic Idiopathic Jaundice (Dubin Johnson Syndrome)
12/2003 - 11/2002
2Type 2 Diabetes Mellitus (MODY)
04/2003 - 08/2002
1Chemical and Drug Induced Liver Injury
10/2022
1Neural Tube Defects (Exencephaly)
01/2022
1Megaloblastic Anemia
01/2022
1Dengue (Dengue Fever)
10/2021
1Viremia
10/2021
1progressive familial intrahepatic 2 Cholestasis
01/2017
1Cerivastatin-Induced Rhabdomyolysis
10/2016
1Pruritus (Itching)
05/2014
1Virus Diseases (Viral Diseases)
01/2014
1Necrosis
12/2011
1Atherosclerosis
04/2011

Drug/Important Bio-Agent (IBA)

55Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2003
21Pharmaceutical PreparationsIBA
01/2022 - 01/2003
10Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2022 - 01/2005
9Multidrug Resistance-Associated Protein 2IBA
11/2010 - 05/2002
8Multidrug Resistance-Associated ProteinsIBA
01/2016 - 01/2007
8Member 11 Subfamily B ATP Binding Cassette TransporterIBA
06/2012 - 04/2005
7Peptides (Polypeptides)IBA
01/2016 - 09/2005
7ATP-Binding Cassette Transporters (ABC Transporters)IBA
07/2012 - 01/2003
6Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2018 - 10/2004
6Messenger RNA (mRNA)IBA
07/2015 - 10/2003
5XenobioticsIBA
01/2018 - 01/2005
5AnionsIBA
11/2013 - 09/2005
44-phenylbutyric acid (Buphenyl)FDA Link
05/2014 - 09/2010
4Bile Acids and Salts (Bile Acids)IBA
06/2012 - 09/2006
3GlucuronidesIBA
01/2022 - 03/2005
3Irinotecan (Camptosar)FDA LinkGeneric
08/2017 - 01/2002
3Adenosine Triphosphate (ATP)IBA
07/2012 - 01/2007
3EstersIBA
05/2012 - 02/2008
3Mitoxantrone (Novantrone)FDA LinkGeneric
06/2010 - 01/2005
3Excipients (Suspending Agents)IBA
03/2009 - 07/2007
3Sulfates (Sulfates, Inorganic)IBA
11/2007 - 03/2005
3Hypoglycemic Agents (Hypoglycemics)IBA
02/2007 - 08/2002
2Docetaxel (Taxotere)FDA Link
10/2015 - 05/2008
2Oseltamivir (Tamiflu)FDA Link
01/2014 - 02/2008
22- amino- 3- (4- ((5- amino- 2- phenylbenzo(d)oxazol- 7- yl)methoxy)- 3,5- dichlorophenyl)propanoic acidIBA
09/2013 - 01/2012
2Amino Acid Transport Systems (Amino Acid Transporter)IBA
09/2013 - 01/2012
2Sulfasalazine (Azulfidine)FDA LinkGeneric
01/2013 - 07/2012
2AcidsIBA
05/2012 - 11/2010
2Probenecid (Benemid)FDA LinkGeneric
12/2011 - 09/2002
2Pravastatin (Pravachol)FDA LinkGeneric
12/2010 - 02/2009
2Cytochrome P-450 CYP3AIBA
01/2010 - 05/2008
2ProdrugsIBA
02/2008 - 04/2005
2EdaravoneIBA
11/2007 - 08/2007
2Free Radical ScavengersIBA
11/2007 - 08/2007
2BilirubinIBA
05/2007 - 09/2005
2Complementary DNA (cDNA)IBA
02/2007 - 06/2003
2EnzymesIBA
05/2006 - 09/2002
2ATP-Binding Cassette Sub-Family B Member 4IBA
09/2005 - 03/2005
2Cisplatin (Platino)FDA LinkGeneric
12/2003 - 05/2002
2Metformin (Glucophage)FDA LinkGeneric
04/2003 - 08/2002
2BiguanidesIBA
04/2003 - 08/2002
2Antineoplastic Agents (Antineoplastics)IBA
02/2002 - 01/2002
1glutathione S-transferase M1IBA
10/2022
1Glutathione Transferase (Glutathione S-Transferase)IBA
10/2022
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2022
1Antiviral Agents (Antivirals)IBA
10/2021
1Acetyl-CoA CarboxylaseIBA
10/2021
1soraphen AIBA
10/2021
1Atorvastatin (Lipitor)FDA Link
12/2019
1cerivastatin (Kazak)FDA Link
07/2018
1Biomarkers (Surrogate Marker)IBA
08/2017
1Clopidogrel (Plavix)FDA Link
10/2016
1Cytochrome P-450 CYP2C8IBA
10/2016
1CationsIBA
01/2016
1Organic Anion TransportersIBA
01/2016
1Therapeutic UsesIBA
05/2014
1Chlorpromazine (Thorazine)FDA Link
03/2014
1ClathrinIBA
03/2014
1Poly CIBA
01/2014
1vorozoleIBA
09/2013
1Organic Cation Transporter 2IBA
09/2013
1Essential Amino AcidsIBA
09/2013
1Anastrozole (Arimidex)FDA LinkGeneric
09/2013
1Creatine Kinase (Creatine Phosphokinase)IBA
01/2013
1GW 4064IBA
06/2012
116- tolyl- 17,18,19,20- tetranorisocarbacyclinIBA
05/2012

Therapy/Procedure

3Therapeutics
01/2017 - 12/2003
1Intravenous Infusions
10/2021